46-Dioxoheptanoic acid( Succinylacetone )

Catalog No. M21430 CAS No. 51568-18-4

46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

46-Dioxoheptanoic acid
Note

Research use only, not for human use.
Brief Description

46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
Description

46-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
In Vitro

4,6-Dioxoheptanoic acid (Succinylacetone, SA) is examined with regard to its ability to a) inhibit the second enzyme of the heme pathway, δ-aminolevulinic acid (ALA) dehydratase, b) lower the heme concentration, and c) inhibit cell growth of murine erythroleukemia (MEL) cells in culture.
In Vivo

——
Synonyms

Succinylacetone
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

51568-18-4
Formula Weight

158.15
Molecular Formula

C7H10O4
Purity

>98% (HPLC)
Solubility

DMSO:1 mg/mL (632.31 mM)
SMILES

CC(CC(CCC(O)=O)=O)=O
Chemical Name

46-dioxoheptanoic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ebert PS et al. Succinylacetone a potent inhibitor of heme biosynthesis: effect on cell growth heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88(4):1382-90.

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